Whenever MHT began to be used, extremely plans consisted of estrogen by yourself. On the seventies, it had been revealed that the the means to access estrogen-by yourself cures are with the risk of endometrial cancer [step 1,2]. Progestagens was basically then placed into new arrangements so you can contradict the results from estrogens and give a wide berth to endometrial cancers [step 3,4].

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